SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549
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                        SCHEDULE 13D/A3 (Amendment No. 3)
          Under the Securities Exchange Act of 1934 (Amendment No. 3)*

                               DOR BioPharma, Inc.
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                                (Name of Issuer)

                                  Common Stock
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                         (Title of Class of Securities)

                                   452916 40 6
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                                 (CUSIP Number)

                                William F. Daniel
                              Elan Corporation, plc
                                  Lincoln House
                                  Lincoln Place
                                Dublin 2, Ireland
                                (353) 1-709-4000

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            (Name, Address and Telephone Number of Person Authorized
                     to Receive Notices and Communications)


                                February 12, 2004
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             (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of ss.ss. 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box [ ].

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Rule 240.13d-7 for other
parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).






                                  Page 1 of 7





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CUSIP No.  452916 40 6
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      (1)         NAME OF REPORTING PERSONS
                  Elan Corporation, plc
                  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
                  N/A
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      (2)         CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See
                  Instructions) (a) [ ]
                                (b) [ ]
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      (3)         SEC USE ONLY

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      (4)         SOURCE OF FUNDS (See Instructions) WC
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      (5)         CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
                  PURSUANT TO ITEMS 2(d) or 2(e)  [  ]
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      (6)         CITIZENSHIP OR PLACE OF ORGANIZATION Ireland
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   Number of      (7)    SOLE VOTING POWER
     Shares              -0-  (See Item 5)
                  --------------------------------------------------------------
  Beneficially    (8)    SHARED VOTING POWER
     Owned               3,970,712  (See Item 5)
                  ------ -------------------------------------------------------
    by Each       (9)    SOLE DISPOSITIVE POWER
   Reporting             -0-  (See Item 5)
                  ------ -------------------------------------------------------
  Person With     (10)   SHARED DISPOSITIVE POWER
                           3,970,712  (See Item 5)
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      (11)        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                  3,970,712 (See Item 5)
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      (12)        CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
                  CERTAIN SHARES (See Instructions)  [  ]
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      (13)        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 10.7% (See
                  Item 5)
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      (14)        TYPE OF REPORTING PERSON (See Instructions) CO
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CUSIP No.  452916 40 6
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      (1)         NAME OF REPORTING PERSONS
                  Elan International Services, Ltd.
                  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
                  N/A
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      (2)         CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See
                  Instructions) (a) [ ]
                                (b) [ ]
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      (3)         SEC USE ONLY

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      (4)         SOURCE OF FUNDS (See Instructions) WC
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      (5)         CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
                  PURSUANT TO ITEMS 2(d) or 2(e)  [  ]
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      (6)         CITIZENSHIP OR PLACE OF ORGANIZATION Bermuda
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   Number of      (7)    SOLE VOTING POWER
     Shares              -0-  (See Item 5)
                  --------------------------------------------------------------
  Beneficially    (8)    SHARED VOTING POWER
     Owned               3,970,712  (See Item 5)
                  --------------------------------------------------------------
    by Each       (9)    SOLE DISPOSITIVE POWER
   Reporting             -0-  (See Item 5)
                  --------------------------------------------------------------
  Person With     (10)   SHARED DISPOSITIVE POWER
                         3,970,712  (See Item 5)
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      (11)        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                  3,970,712 (See Item 5)
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      (12)        CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
                  CERTAIN SHARES (See Instructions)  [  ]
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      (13)        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 10.7% (See
                  Item 5)
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      (14)        TYPE OF REPORTING PERSON (See Instructions) CO
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CUSIP No.  452916 40 6
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      (1)         NAME OF REPORTING PERSONS
                  Elan Pharmaceutical Investments, Ltd.
                  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
                  N/A
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      (2)         CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See
                  Instructions) (a) [ ]
                                (b) [ ]
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      (3)         SEC USE ONLY

--------------------------------------------------------------------------------
      (4)         SOURCE OF FUNDS (See Instructions) WC
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      (5)         CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
                  PURSUANT TO ITEMS 2(d) or 2(e)  [  ]
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      (6)         CITIZENSHIP OR PLACE OF ORGANIZATION Bermuda
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   Number of      (7)    SOLE VOTING POWER
     Shares              -0- (See Item 5)
                  --------------------------------------------------------------
  Beneficially    (8)    SHARED VOTING POWER
     Owned               3,470,712  (See Item 5)
                  --------------------------------------------------------------
    by Each       (9)    SOLE DISPOSITIVE POWER
   Reporting             -0- (See Item 5)
                  --------------------------------------------------------------
  Person With     (10)   SHARED DISPOSITIVE POWER
                         3,470,712  (See Item 5)
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      (11)        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                  3,470,712 (See Item 5)
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      (12)        CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
                  SHARES (See Instructions)  [  ]
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      (13)        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 9.3% (See
                  Item 5)
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      (14)        TYPE OF REPORTING PERSON (See Instructions) CO
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Item 1. Security and Issuer.

     Item 1 of the Schedule 13D is hereby amended and restated in its entirety
as follows:

     This Amendment No. 3 amends the Schedule 13D filed with the Securities and
Exchange Commission (the "Commission") on February 4, 1998, as amended by the
Schedule 13D/A1 filed with the Commission on May 23, 2002 and by Schedule 13D/A2
filed with the Commission on February 6, 2004 (as so amended, the "Schedule
13D") relating to the common stock, par value $.001 per share (the "Common
Stock"), of DOR BioPharma, Inc., a Delaware corporation (the "Issuer"). The name
and address of the principal executive offices of the Issuer is DOR BioPharma,
Inc., 1691 Michigan Ave., Suite 435, Miami, FL 33139.

Item 5. Interest in Securities of Issuer.

     Item 5 of the Schedule 13D is hereby amended and restated in its entirety
as follows:

     (a) As of February 13, 2004, Elan (indirectly through its ownership of EIS
and EPIL) and EIS (directly in respect of 500,000 shares of Common Stock and
indirectly through its ownership of EPIL) each beneficially owned 3,970,712
shares of Common Stock (including 2,501,811 shares of Common Stock issuable upon
conversion of the Series B Convertible Preferred Stock), representing 10.7% of
the outstanding shares of Common Stock (based on 34,636,908 shares of Common
Stock outstanding as of November 1, 2003 as reported in the Issuer's Form 10-QSB
for the quarterly period ended September 30, 2003). As of February 13, 2004,
EPIL beneficially owned 3,470,712 shares of Common Stock (including 2,501,811
shares of Common Stock issuable upon conversion of the Series B Convertible
Preferred Stock, representing 9.3% of the outstanding shares of Common Stock
(based on 34,636,908 shares of Common Stock outstanding as of November 1, 2003
as reported in the Issuer's Form 10-QSB for the quarterly period ended September
30, 2003).

     (b) As of February 13, 2004, Elan (indirectly through its ownership of EIS
and EPIL) and EIS (directly in respect of 500,000 shares of Common Stock and
indirectly through its ownership of EPIL) each had the shared voting and
dispositive power over 3,970,712 shares of Common Stock (including 2,501,811
shares of Common Stock issuable upon conversion of the Series B Convertible
Preferred Stock). As of February 13, 2004, EPIL had the shared voting and
dispositive power over 3,470,712 shares of Common stock (including 2,501,811
shares of Common Stock issuable upon conversion of the Series B Convertible
Preferred Stock).




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     (c) On February 11, 2004 and February 12, 2004, EPIL sold an aggregate of
583,979 shares of Common Stock in open market transactions as listed below:


       Date of Sale              Amount             Price Per Share
       ------------              ------             ---------------

         02/11/04                52,879                 $1.11
         02/11/04                81,000                 $1.10
         02/11/04                10,400                 $1.09
         02/11/04                16,600                 $1.08
         02/11/04                 4,800                 $1.07
         02/11/04                44,900                 $1.06
         02/11/04                106,900                $1.05
         02/12/04                11,000                 $1.06
         02/12/04                69,200                 $1.05
         02/12/04                 5,600                 $1.02
         02/12/04                180,700                $1.01

     (d) None.

     (e) Not applicable.




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                                   SIGNATURES

     After reasonable inquiry and to the best of its knowledge and belief, each
of the undersigned certifies that the information set forth in this statement is
true, complete and correct.

Date:    February 13, 2004

                                 ELAN CORPORATION, PLC

                                 By:  /s/ William F. Daniel
                                      ------------------------------------
                                      Name:  William F. Daniel
                                      Title:    Executive Vice President
                                                and Secretary

                                 ELAN INTERNATIONAL SERVICES, LTD.

                                 By:  /s/ Debra Moore Buryj
                                      ------------------------------------
                                      Name:  Debra Moore Buryj
                                      Title:    Vice President


                                 ELAN PHARMACEUTICAL INVESTMENTS, LTD.

                                 By:  /s/ Debra Moore Buryj
                                      ------------------------------------
                                      Name:  Debra Moore Buryj
                                      Title:    Vice President






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