SEC 1745 (3-98)
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                                   UNITED STATES
                         SECURITIES AND EXCHANGE COMMISSION
                              Washington, D.C. 20549


SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. 01)*

Acadia Pharmaceuticals Inc.

COMMON

004225108

12-31-2008

Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
[ X ] Rule 13d-1(b)
[   ] Rule 13d-1(c)
[   ] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which
would alter the disclosures provided in a prior cover page. The information
required in the remainder of this cover page shall not be deemed to be
"filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see
the Notes).


CUSIP No.   004225108


1.Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only)

          Delaware Management Holdings  23-2693133
...................................................................

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)................................................................
(b)................................................................

3.SEC Use Only ....................................................


4.Citizenship or Place of Organization

State of Delaware
....................................................................



Number of                5. Sole Voting Power 	     1,907,758
Shares                   6. Shared Voting Power      2,243
Beneficially             7. Sole Dispositive Power   1,929,749
Owned by                 8. Shared Dispositive Power 00
Each Reporting
Person With


9. Aggregate Amount Beneficially Owned by Each Reporting Person 1,929,749

10. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See
Instructions)
11. Percent of Class Represented by Amount in Row (11)  5.2%
12. Type of Reporting Person (See Instructions)

HC



CUSIP No.   004225108


1.Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only)

          Delaware Management Business Trust  23-2859589
...................................................................

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)................................................................
(b)................................................................

3.SEC Use Only ....................................................


4.Citizenship or Place of Organization

State of Delaware
....................................................................



Number of                5. Sole Voting Power 	     1,907,758
Shares                   6. Shared Voting Power      2,243
Beneficially             7. Sole Dispositive Power   1,929,749
Owned by                 8. Shared Dispositive Power 00
Each Reporting
Person With


9. Aggregate Amount Beneficially Owned by Each Reporting Person 1,929,749

10. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See
Instructions)
11. Percent of Class Represented by Amount in Row (11)  5.2%
12. Type of Reporting Person (See Instructions)

IA


Item 1.

     (a) Acadia Pharmaceuticals Inc.
     (b) 3911 Sorrento Valley Blvd

         San Diego
         CA
         92121

 Item 2.

     (a) Delaware Management Holdings
     (b) 2005  Market Street

	     Philadelphia
	     PA
	     19103
    (c)  State of Delaware
    (d)  COMMON
    (e)  004225108

 Item 3.
         If this statement is filed pursuant to 240.13d-1(b) or
         240.13d-2(b) or (c), check whether the person filing is a:

         (a) [   ] Broker or dealer registered under section 15 of the
                   Act (15 U.S.C. 78o).
         (b) [   ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C.
                   78c).
         (c) [   ] Insurance company as defined in section 3(a)(19) of the
                   Act (15 U.S.C. 78c).
         (d) [   ] Investment company registered under section 8 of the
                   Investment Company Act of 1940 (15 U.S.C 80a-8).
         (e) [   ] An investment adviser in accordance with
                   240.13d-1(b)(1)(ii)(E);
         (f) [   ] An employee benefit plan or endowment fund in accordance
                   with 240.13d-1(b)(1)(ii)(F);
         (g) [ X ] A parent holding company or control person in accordance
                   with 240.13d-1(b)(1)(ii)(G);
         (h) [   ] A savings associations as defined in Section 3(b) of the
                   Federal Deposit Insurance Act (12 U.S.C. 1813);
         (i) [   ] A church plan that is excluded from the definition of an
                   investment company under section 3(c)(14) of the
                   Investment Company Act of 1940 (15 U.S.C. 80a-3);
         (j) [   ] Group, in accordance with 240.13d-1(b)(1)(ii)(J).

 Item 4.
         Ownership.
 Provide the following information regarding the aggregate number and
 percentage of the class of securities of the issuer identified in Item 1.

         (a) Amount beneficially owned: 1,929,749

         (b) Percent of class: 5.2

         (c) Number of shares as to which the person has:
             (i) Sole power to vote or to direct the vote   1,907,758
            (ii) Shared power to vote or to direct the vote 2,243
           (iii) Sole power to dispose or to direct the
                 disposition of                             1,929,749
            (iv) Shared power to dispose or to direct the
                 disposition  of                            00

 Item 5.
         Ownership of Five Percent or Less of a Class
 If this statement is being filed to report the fact that as of the date
 hereof the reporting person has ceased
 to be the beneficial owner of more than five percent of the class of
 securities, check the following [N].

 Item 6.
         Ownership of More than Five Percent on Behalf of Another Person.
 If any other person is known to have the right to receive or the power to
 direct the receipt of dividends from, or the proceeds from the sale of,
 such securities, a statement to that effect should be included in
 response to this item and, if such interest relates to more than five
 percent of the class, such person should be identified. A listing of the
 shareholders of an investment company registered under the Investment
 Company Act of 1940 or the beneficiaries of employee benefit plan, pension
 fund or endowment fund is not required.

 Item 7.
         Identification and Classification of the Subsidiary Which Acquired
 the Security Being Reported on By the Parent Holding Company.
 If a parent holding company has filed this schedule, pursuant to
 Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit
 stating the identity and the Item 3 classification of the relevant
 subsidiary. If a parent holding company has filed this schedule pursuant
 to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the
 identification of the relevant subsidiary.

LINCOLN NATIONAL CORP IS THE ULTIMATE PARENT OF DELAWARE MANAGEMENT
BUSINESS TRUST.

 Item 8.
         Identification and Classification of Members of the Group
 If a group has filed this schedule pursuant to  240.13d-1(b)(1)(ii)(J), so
 indicate under Item 3(j) and attach an exhibit stating the identity and
 Item 3 classification of each member of the group. If a group has
 filed this schedule pursuant to 240.13d-1(c) or 240.13d-1(d), attach an
 exhibit stating the identity of each member of the group.

See Agreement to File Joint Acquisition Statements attached

 Item 9.
         Notice of Dissolution of Group

	N/A

 Notice of dissolution of a group may be furnished as an exhibit stating
 the date of the dissolution and that all further filings with respect to
 transactions in the security reportedon will be filed, if required, by
 members of the group, in their individual capacity. See Item 5.

 Item 10.
         Certification

         (a)  The following certification shall be included if the
              statement is filed pursuant to 240.13d-1(b):

                 By signing below I certify that, to the best of my
                 knowledge and belief, the securities referred to above were
                 acquired and are held in the ordinary course of business
                 and were not acquired and are not held for the purpose of
                 or with the effect of changing or influencing the control
                 of the issuer of the securities and were not acquired and
                 are not held in connection with or as a participant in any
                 transaction having that purpose or effect.

         (b) The following certification shall be included if the statement
             is filed pursuant to  240.13d-1(c):

                 By signing below I certify that, to the best of my
                 knowledge and belief, the securities referred to above
                 were not acquired and are not held for the purpose of or
                 with the effect of changing or influencing the control of
                 the issuer of the securities and were not acquired and are
                 not held in connection with or as a participant in any
                 transaction having that purpose or effect.

Date      01-30-2009

Signature  /s/ Brian L. Murray

Name/Title     Brian L. Murray/Chief Compliance Officer



After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct. The original statement shall be signed by each person on whose
behalf the statement is filed or his authorized representative. If the
statement is signed on behalf of a person by his authorized representative
other than an executive officer or general partner of the filing person,
evidence of the representative's authority to sign on behalf of such person
shall be filed with the statement, provided, however, that a power of
attorney for this purpose which is already on file with the Commission may
be incorporated by reference.The name and any title of each person who
signs the statement shall be typed or printed beneath his signature.