SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                -----------------

                                  SCHEDULE 13G
                                 (Rule 13d-102)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b),(c) AND (d) AND AMENDMENTS THERETO FILED
                            PURSUANT TO RULE 13d-2(b)
                               (Amendment No. )1


                                 NITROMED, INC.
          ------------------------------------------------------------
                                (Name of Issuer)


                          Common Stock, $.01 par value
          ------------------------------------------------------------

                         (Title of Class of Securities)


                                   654798 50 3
          ------------------------------------------------------------
                                 (CUSIP Number)


                                November 5, 2003
          ------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [ ] Rule 13d-1(b)

         [ ] Rule 13d-1(c)

         [X] Rule 13d-1(d)


--------------------------
     1 The  remainder  of this cover  page  shall be filled out for a  reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter  disclosures  provided in a prior cover page. The information  required on
the  remainder  of this cover  page  shall not be deemed to be  "filed"  for the
purpose  of  Section  18 of the  Securities  Exchange  Act of 1934 or  otherwise
subject to the  liabilities  of that  section of the Act but shall be subject to
all other provisions of the Act.




CUSIP No. 654798 50 3                                        Page 2 of 6 Pages


--------------------------------
1. NAMES OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

                  Johnson & Johnson
                  22-1024240
--------------------------------
2.   CHECK THE APPROPRIATE BOX IF               (a) [ ]
     A MEMBER OF A GROUP                        (b) [ ]

--------------------------------
3.   SEC USE ONLY
--------------------------------
4.   CITIZENSHIP OR PLACE OF ORGANIZATION

         New Jersey
--------------------------------
   NUMBER OF                        5.   SOLE VOTING POWER
    SHARES
 BENEFICIALLY                                      -0-
   OWNED BY
     EACH                           6.   SHARED VOTING POWER
  REPORTING
 PERSON WITH
                                            1,342,207 shares of Common Stock
                                    _____________________
                                    7.   SOLE DISPOSITIVE POWER

                                                   -0-
                                    _____________________
                                    8. SHARED DISPOSITIVE POWER

                                            1,342,207 shares of Common Stock
--------------------------------
9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     1,342,207 shares of Common Stock

--------------------------------
10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                     [  ]
--------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  5.25%
--------------------------------
12. TYPE OF REPORTING PERSON

                  CO
--------------------------------



CUSIP No. 654798 50 3                                        Page 3 of 6 Pages


--------------------------------
1. NAMES OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

                  Johnson & Johnson Development Corporation
                  22-2007137
--------------------------------

2.   CHECK THE APPROPRIATE BOX IF               (a) [ ]
     A MEMBER OF A GROUP                        (b) [ ]
--------------------------------
3. SEC USE ONLY
--------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION

         New Jersey
--------------------------------
   NUMBER OF                        5.   SOLE VOTING POWER
    SHARES
 BENEFICIALLY                                      -0-
   OWNED BY
      EACH                          6.   SHARED VOTING POWER
   REPORTING
    PERSON                                  1,342,207 shares of Common Stock
     WITH
                                    _____________________
                                    7. SOLE DISPOSITIVE POWER

                                                   -0-
                                    _____________________
                                    8. SHARED DISPOSITIVE POWER

                                            1,342,207 shares of Common Stock
--------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

   1,342,207 shares of Common Stock

--------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                     [  ]
--------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  5.25%
--------------------------------
12. TYPE OF REPORTING PERSON

                  CO
--------------------------------




CUSIP No. 654798 50 3                                        Page 4 of 6 Pages

                                  Schedule 13G
                                  ------------

ITEM 1(a) -             NAME OF ISSUER:

                        NitroMed, Inc.

ITEM 1(b) -             ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
                        12 Oak Park Drive
                        Bedford, MA 01730

ITEM 2(a) -             NAME OF PERSON FILING:

         This statement is being filed by Johnson & Johnson, a New Jersey
corporation ("J&J"), and Johnson & Johnson Development Corporation, a New Jersey
corporation ("JJDC"). JJDC is a wholly-owned subsidiary of J&J. The securities
reported herein as being held by J&J and JJDC are directly beneficially owned by
JJDC. J&J may be deemed to indirectly beneficially own the securities that are
directly beneficially owned by JJDC.

ITEM 2(b) -             ADDRESS OF PRINCIPAL BUSINESS OFFICE:

                        One Johnson & Johnson Plaza
                        New Brunswick, NJ 08933

ITEM 2(c) -             CITIZENSHIP:

                        J&J: New Jersey
                        JJDC: New Jersey

ITEM 2(d) -             TITLE OF CLASS OF SECURITIES:

                        Common Stock, $.01 par value per share ("Common Stock")

ITEM 2(e) -             CUSIP NUMBER:

                        654798 50 3

ITEM 3 -                STATEMENTS FILED PURSUANT TO RULES 13D-1(B) OR
                        13D-2(B) OR (C):

                        Not applicable.

ITEM 4 -                OWNERSHIP:

                        (a) Amount Beneficially Owned:

                        J&J:  1,342,207 shares of Common Stock
                        JJDC:  1,342,207 shares of Common Stock

                        (b) Percent of Class:

                        J&J: 5.25%
                        JJDC: 5.25%




CUSIP No. 654798 50 3                                        Page 5 of 6 Pages



                        (c) Number of shares as to which such person has:

                        (i) sole power to vote or to direct the vote: -0-

                        (ii) shared power to vote or to direct the vote:

                        J&J:  1,342,207 shares of Common Stock
                        JJDC:  1,342,207 shares of Common Stock

                        (iii) sole power to dispose or to direct the
                        disposition of: -0-

                        (iv) shared power to dispose or to direct the
                        disposition of:

                        J&J:  1,342,207 shares of Common Stock
                        JJDC:  1,342,207 shares of Common Stock


ITEM 5 -        OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:

                        Not applicable.

ITEM 6 -        OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:

                        Not applicable.

ITEM 7 -        IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
                ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT COMPANY:

                        Not applicable.

ITEM 8 -        IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:

                        Not applicable.

ITEM 9 -        NOTICE OF DISSOLUTION OF GROUP:

                        Not applicable.

ITEM 10 -       CERTIFICATION:

                        Not applicable.



CUSIP No. 654798 50 3                                        Page 6 of 6 Pages


                                    SIGNATURE

        After  reasonable  inquiry and to the best of my  knowledge  and belief
I certify that the information  set forth in this statement is true,  complete
and correct.

                                   JOHNSON & JOHNSON


                                   By  /s/ MICHAEL H. ULLMANN
                                     ---------------------------
                                   Name: Michael H. Ullmann
                                   Title: Secretary

Dated: February 11, 2004

                                   JOHNSON & JOHNSON DEVELOPMENT CORPORATION


                                   By /s/ ERIC B. JUNG
                                     ---------------------------
                                   Name: Eric B. Jung
                                   Title: Secretary

Dated: February 11, 2004