Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Chang William H
  2. Issuer Name and Ticker or Trading Symbol
Semler Scientific, Inc. [SMLR]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O SEMLER SCIENTIFIC, INC., 2330 NW EVERETT ST.
3. Date of Earliest Transaction (Month/Day/Year)
02/26/2014
(Street)

PORTLAND, OR 97210
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/26/2014   C(1)   417,781 A (1) 537,066 I By Chang Family Trust
Common Stock 02/26/2014   C(1)   64,583 A (1) 601,649 I By Chang Family Trust
Common Stock 02/26/2014   C(1)   41,667 A (1) 634,316 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   38,889 A $ 4.5 682,205 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   83,334 A $ 4.5 765,539 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   92,501 A $ 4.5 858,040 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   54,167 A $ 4.5 912,207 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   37,500 A $ 4.5 949,707 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   37,500 A $ 4.5 987,207 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   44,445 A $ 4.5 1,031,652 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   20,844 A $ 4 1,052,496 I By Chang Family Trust
Common Stock 02/26/2014   M(2)   48,437 A $ 4 1,100,933 I By Chang Family Trust
Common Stock 02/26/2014   F(2)   286,460 D $ 7 814,473 I By Chang Family Trust

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Convertible Preferred Stock (1) 02/26/2014   C(1)     417,781   (1)   (1) Common Stock 417,781 $ 0 0 I By Chang Family Trust
Series A-1 Convertible Preferred Stock (1) 02/26/2014   C(1)     64,583   (1)   (1) Common Stock 64,583 $ 0 0 I By Chang Family Trust
Series A-2 Convertible Preferred Stock (1) 02/26/2014   C(1)     41,667   (1)   (1) Common Stock 41,667 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     38,889 07/01/2013 07/31/2016 Common Stock 38,889 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     83,334 08/31/2012 06/30/2015 Common Stock 83,334 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     92,501 07/01/2012 06/30/2016 Common Stock 92,501 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     54,167 06/07/2012 06/30/2015 Common Stock 54,167 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     37,500 06/07/2012 08/31/2021 Common Stock 37,500 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     37,500 06/07/2012 05/31/2021 Common Stock 37,500 $ 0 0 I By Chang Family Trust
Series A Preferred Stock Warrant (right to buy) $ 4.5 02/26/2014   M(2)     44,445 06/07/2012 01/31/2016 Common Stock 44,445 $ 0 0 I By Chang Family Trust
Series A-1 Preferred Stock Warrant (right to buy) $ 4 02/26/2014   M(2)     20,844 06/07/2012 01/31/2016 Common Stock 20,844 $ 0 0 I By Chang Family Trust
Series A-1 Preferred Stock Warrant (right to buy) $ 4 02/26/2014   M(2)     48,437 06/07/2012 06/30/2015 Common Stock 48,437 $ 0 0 I By Chang Family Trust

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Chang William H
C/O SEMLER SCIENTIFIC, INC.
2330 NW EVERETT ST.
PORTLAND, OR 97210
  X   X    

Signatures

 /s/ Douglas Murphy-Chutorian, attorney-in-fact   02/27/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These securities automatically converted into Issuer's common stock on a one-for-one basis upon consummation of Issuer's initial public offering ("IPO") and had no expiration date.
(2) These securities were cashlessly exercised immediately prior to Issuer's IPO and automatically converted into shares of Issuer's common stock on a one-for-one basis.

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