UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K
                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934



                Date of Report (Date of earliest event reported):
                                 April 30, 2003


                         AVANT IMMUNOTHERAPEUTICS, INC.
               (Exact name of registrant as specified in charter)


         Delaware                      0-15006                  13-3191702
(State or other jurisdiction    (Commission file number)       (IRS employer
    of incorporation)                                       identification no.)


                                119 Fourth Avenue
                          Needham, Massachusetts 02494
               (Address of principal executive offices) (Zip code)


               Registrant's telephone number, including area code:
                                 (781) 433-0771









ITEM 7.     FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

            (c) Exhibits.

                99.1   The Company's Press Release dated April 30, 2003.

ITEM 9.    REGULATION FD DISCLOSURE..

               The following information is furnished under Item 12 of Form 8-K
               "Results of Operations and Financial Condition". This information
               is being furnished and shall not be deemed "filed" for the
               purposes of Section 18 of the Securities Exchange Act of 1934 or
               otherwise subject to the liabilities of that Section. The
               information in this Current Report on Form 8-K shall not be
               incorporated by reference into any registration statement or
               other document pursuant to the Securities Act of 1933 as amended.

               On April 30, 2003, the Company issued a press release which is
               attached to this Form 8-K as Exhibit 99.1.










                                   SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                    AVANT IMMUNOTHERAPEUTICS, INC.



Date:  April 30, 2003               By:   /s/ Avery W. Catlin
                                       --------------------------------------
                                         Avery W. Catlin
                                         Senior Vice President and
                                         Chief Financial Officer









                                  EXHIBIT INDEX


Exhibit                                                         Sequential
Number                       Description                        Page Number
-------                      -----------                        -----------
99.1                   The Company's Press Release                  6
                       dated April 30, 2003