Filed Pursuant to
Rule 424 (b) (3) and (c)
File No. 333-54350

GILEAD SCIENCES, INC.

$250,000,000 Principal Amount
5% Convertible Subordinated Notes due December 15, 2007
and
Shares of Common Stock Issuable upon Conversion of the Notes

        This prospectus supplement should be read in conjunction with the prospectus dated February 9, 2001, which is to be delivered with this prospectus supplement.

        SEE "RISK FACTORS" BEGINNING ON PAGE 6 OF THE PROSPECTUS TO READ ABOUT FACTORS YOU SHOULD CONSIDER BEFORE BUYING THE NOTES OR OUR COMMON STOCK.

        Neither the Securities and Exchange Commission nor any other regulatory body has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense.


        The table and related notes, and the paragraph immediately following the table and related notes, appearing in the prospectus under the heading "Selling Securityholders" is superseded by the following table and related notes, and the following paragraph immediately following the table and related notes:

Name
   Principal
Amount of
Notes
Beneficially
Owned and
Offered(1)
   Common Stock
Beneficially
Owned(1)(2)
   Common Stock
Offered(1)(2)
   Principal
Amount of
Notes Owned
After
Completion of
Offering
   Common Stock
Owned After
Completion of
Offering
1976 Distribution Trust FBO A.R. Lander / Zinterhofer   14,000   569   569   0   0
1976 Distribution Trust FBO Jane A. Lander   14,000   569   569   0   0
American Motorist Insurance Company   489,000   19,908   19,908   0   0
Arapahoe County Colorado   48,000   1,954   1,954   0   0
Bankgesellschaft Berlin AG   4,500,000   183,206   183,206        
British Virgin Islands Social Security Board   36,000   1,465   1,465   0   0
Brown & Williamson Tobacco Retirement Trust   25,000   1,017   1,017   0   0
Century National Insurance Company   500,000   20,356   20,356   0   0
City of New Orleans   201,000   8,183   8,183   0   0
Credit Suisse First Boston Corporation   100,000   4,071   4,071   0   0
Deutsche Banc Alex Brown Inc   4,775,000   194,402   194,402   0   0
Employee Benefit Convertible Securities Fund (Custodian DTC #955 Bank of America Personal Trust)   75,000   3,053   3,053   0   0
Fidelity Financial Trust: Fidelity Convertible Securities Fund   1,500,000   61,068   61,068   0   0
Forest Alternative Strategies Fund II L.P. ASM   25,000   1,017   1,017   0   0
Forest Global Convertible Fund A-5   1,755,000   71,450   71,450   0   0
Highbridge International LLC   6,852,000   278,961   278,961   0   0
KBC Financial Products USA   2,500,000   101,781   101,781   0   0
Lehman Brothers Inc.   7,225,000   294,147   294,147   0   0
Lipper Convertibles L.P.   1,000,000   40,712   40,712   0   0
LLT Limited   100,000   4,071   4,071   0   0
Local Initiatives Support Corporation   46,000   1,872   1,872   0   0
Merrill Lynch Insurance Group   246,000   10,015   10,015   0   0
Nabisco Holdings   29,000   1,180   1,180   0   0
New Orleans Firefighters Pension / Relief Fund   106,000   4,315   4,315   0   0
New York Life Insurance and Annuity Corporation   1,000,000   40,712   40,712   0   0
New York Life Insurance Company   9,000,000   366,412   366,412   0   0
Occidental Petroleum Corporation   194,000   7,898   7,898   0   0
Pacific Life Insurance Company   1,000,000   40,712   40,712   0   0
Pro-Mutual   685,000   27,888   27,888   0   0
Raytheon Master Pension Trust   529,000   21,536   21,536   0   0
RBC Capital Services, Inc. c/o Forest Investment Mngt., L.L.C.   20,000   814   814   0   0
RJR Reynolds   92,000   3,745   3,745   0   0
Robertson Stephens   6,000,000   244,274   244,274   0   0
Salomon Brothers Asset Management, Inc.   4,000,000   162,849   162,849   0   0
San Diego County Employees Retirement Association   120,000   4,885   4,885   0   0
SG Cowen Securities Corporation   2,000,000   81,424   81,424   0   0
Shell Pension Trust   428,000   17,424   17,424   0   0
Smithfield Trust Company   10,000   407   407   0   0
State of Maryland Retirement System   2,509,000   83,826   83,826   0   0
The City University of New York   119,000   4,844   4,844   0   0
The Grable Foundation   91,000   3,704   3,704   0   0

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The Grady Hospital Foundation   103,000   4,193   4,193   0   0
Tribeca Investment LLC   8,000,000   325,699   325,699   0   0
Zurich Master Hedge Fund c/o Forest Investment Mngt., L.L.C.   100,000   4,071   4,071   0   0
(1)
Amounts indicated may be in excess of the total amount registered due to sales or transfers exempt from the registration requirements of the Securities Act since the date upon which the selling holders provided to us the information regarding their notes and common stock.

(2)
Unless otherwise noted, represents shares of common stock issuable upon conversion of notes. Gilead's Board of Directors declared a two-for-one split of the outstanding shares of the company's common stock for all holders of record as of the close of business on February 2, 2001 and again on February 14, 2002. Each split was effected in the form of a stock dividend that resulted in a reduction by one-half of the conversion price per share and an increase in the number of shares of common stock issuable upon conversion of the notes on the effective date of each split. As of February 3, 2001, the notes became convertible at a conversion price of $49.125 per share and as of February 15, 2002, the notes became convertible at a conversion price of $24.5625 per share. All stock numbers in this supplement have been adjusted to give effect to each of these two-for-one stock splits.

        With the exception of Lehman Brothers Inc., none of the selling holders nor any of their affiliates, officers, directors or principal equity holders has held any position or office or has had any material relationship with us within the past three years. Lehman Brothers Inc. was an initial purchaser of the notes. The selling holders purchased the notes in private transactions on or after December 13, 2000.

The date of this prospectus supplement is December 20, 2002.

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