UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G


                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                              (AMENDMENT NO. 2)(1)



                               Celsion Corporation
          -------------------------------------------------------------
                                (Name of Issuer)


                     Common Stock, par value $0.01 per share
          -------------------------------------------------------------
                         (Title or Class of Securities)


                                    15117N107
          -------------------------------------------------------------
                                 (CUSIP Number)


                                 August 11, 2005
          -------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [_] Rule 13d-l(b)
         [X] Rule 13d-l(c)
         [_] Rule 13d-1(d)

------------------------
(1)      The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.

         The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).





CUSIP NO. 15117N107                   13G                            PAGE 2 OF 6


--------------------------------------------------------------------------------
1        NAMES OF REPORTING PERSONS
         S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Boston Scientific Corporation
--------------------------------------------------------------------------------
2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
                                                                      (a)   [_]
         N/A                                                          (b)   [_]
--------------------------------------------------------------------------------
3        SEC USE ONLY


--------------------------------------------------------------------------------
4        CITIZENSHIP OR PLACE OF ORGANIZATION

         The State of Delaware
--------------------------------------------------------------------------------
                        5        SOLE VOTING POWER

                                 22,568,637.57
    NUMBER OF           --------------------------------------------------------
      SHARES            6        SHARED VOTING POWER
   BENEFICIALLY
     OWNED BY                    0
       EACH             --------------------------------------------------------
    REPORTING           7        SOLE DISPOSITIVE POWER
      PERSON
       WITH                      22,568,637.57
                        --------------------------------------------------------
                        8        SHARED DISPOSITIVE POWER

                                 0
--------------------------------------------------------------------------------
9        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         22,568,637.57
--------------------------------------------------------------------------------
10       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (SEE INSTRUCTIONS)         [_]

         N/A
--------------------------------------------------------------------------------
11       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

         13.2%
--------------------------------------------------------------------------------
12       TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

         CO
--------------------------------------------------------------------------------




CUSIP NO. 15117N107                   13G                            PAGE 3 OF 6


ITEM 1(A).    NAME OF ISSUER:

              Celsion Corporation, a Delaware Corporation (the "Company")


ITEM 1(B).    ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

              10220-L Old Colombia Road
              Colombia, Maryland 21046-1705


ITEM 2(A).    NAME OF PERSON FILING:

              Boston Scientific Corporation


ITEM 2(B).    ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:

              One Boston Scientific Place, Natick, MA 01760-1537


ITEM 2(C).    CITIZENSHIP:

              The State of Delaware


ITEM 2(D).    TITLE OF CLASS OF SECURITIES:

              Common Stock, par value $0.01 per share (the "shares")


ITEM 2(E).    CUSIP NUMBER:

              15117N107


ITEM 3.       IF THIS STATEMENT IS FILED PURSUANT TO RULES 13D-1(B), OR
              13D-2(B), CHECK WHETHER THE PERSON FILING IS A:

              (a)  [_]  Broker or dealer registered under section 15 of the Act
                        (15 U.S.C. 78o).

              (b)  [_]  Bank as defined in section 3(a)(6) of the Act (15 U.S.C.
                        78c).

              (c)  [_]  Insurance company as defined in section 3(a)(19) of the
                        Act (15 U.S.C. 78c).

              (d)  [_]  Investment company registered under section 8 of the
                        Investment Company Act of 1940 (15 U.S.C 80a-8).




CUSIP NO. 15117N107                   13G                            PAGE 4 OF 6


              (e)  [_]  An investment adviser in accordance with
                        ss.240.13d-1(b)(1)(ii)(E);

              (f)  [_]  An employee benefit plan or endowment fund in accordance
                        with ss.240.13d-1(b)(1)(ii)(F);

              (g)  [_]  A parent holding company or control person in accordance
                        with ss.240.13d-1(b)(1)(ii)(G);

              (h)  [_]  A savings associations as defined in Section 3(b) of the
                        Federal Deposit Insurance Act (12 U.S.C. 1813);

              (i)  [_]  A church plan that is excluded from the definition of an
                        investment company under section 3(c)(14) of the
                        Investment Company Act of 1940 (15 U.S.C. 80a-3);

              (j)  [_]  Group, in accordance with ss.240.13d-l(b)(1)(ii)(J).

ITEM 4.       OWNERSHIP:

              (a)  Amount beneficially owned: 22,568,637.57 shares
              (b)  Percent of class: 13.2%
              (c)  Number of shares as to which such person has:
                   (i)   Sole Power to vote or to direct the vote: 22,568,637.57
                         shares
                   (ii)  Shared power to vote or to direct the vote: 0 shares
                   (iii) Sole power to dispose or to direct the disposition of:
                         22,568,637.57 shares
                   (iv)  Shared power to dispose or to direct the disposition
                         of: 0 shares

On August 11, 2005, Celsion Corporation ("Celsion") issued to the reporting
person a $6,000,000 convertible secured promissory note (the "Note"), the terms
of which permit the reporting person, at any time, to convert all or a portion
of the principal amount of the Note, plus accrued and unpaid interest, into a
maximum of 9,836,065 shares of Celsion common stock. The 9,836,065 shares of
Celsion common stock issuable on conversion of the Note represent approximately
6.1% of the issued and outstanding Celsion common stock, calculated on an
as-issued basis.



ITEM 5.       OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:

              If this statement is being filed to report the fact that as of the
              date hereof the reporting person has ceased to be the beneficial
              owner of more than five percent of the class of securities, check
              the following: [_]






CUSIP NO. 15117N107                   13G                            PAGE 5 OF 6


ITEM 6.       OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:

              Not applicable.


ITEM 7.       IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
              THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY:

              Not applicable.


ITEM 8.       IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:

              Not applicable.


ITEM 9.       NOTICE OF DISSOLUTION OF A GROUP:

              Not applicable.


ITEM 10.      CERTIFICATION:

              By signing below I certify that, to the best of my knowledge and
              belief the securities referred to above were not acquired and are
              not held for the purpose of or with the effect of changing or
              influencing the control of the issuer of the securities and were
              not acquired and are not held in connection with or as a
              participant in any transaction having that purpose or effect.




CUSIP NO. 15117N107                   13G                            PAGE 6 OF 6



                                   SIGNATURE

              After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.


                                             August 17, 2005
                                     ------------------------------
                                                 (Date)


                                     By:  /s/  Lawrence J. Knopf
                                     ------------------------------
                                     Name:   Lawrence J. Knopf
                                     Title:  Vice President and Assistant
                                             General Counsel