SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                               (Amendment No. 4)*




                         PROGENICS PHARMACEUTICALS, INC.
--------------------------------------------------------------------------------
                                (Name of Issuer)



                                  COMMON STOCK
--------------------------------------------------------------------------------
                         (Title of Class of Securities)



                                    743187106
--------------------------------------------------------------------------------
                                 (CUSIP Number)




Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

        [ ]     Rule 13d-1(b)

        [ ]     Rule 13d-1(c)

        [X]     Rule 13d-1(d)


* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).


                                     Page 1




CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Tudor Investment Corporation
        ------------------------------------------------------------------------
            22-2514825
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization  Delaware
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                        2,107,881
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                   2,107,881
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   2,107,881
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9         16.8%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    CO
--------------------------------------------------------------------------------

                                     Page 2


CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Tudor Group Holdings LLC
        ------------------------------------------------------------------------
            13-3862746
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization  Delaware
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                          234,507
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                     234,507
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   234,507
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9         1.9%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    OO
--------------------------------------------------------------------------------

                                     Page 3



CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Paul Tudor Jones, II
        ------------------------------------------------------------------------
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization       USA
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                            546,125
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                        2,342,388
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                       546,125
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                   2,342,388
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   2,888,513
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9        23.1%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    IN
--------------------------------------------------------------------------------

                                     Page 4



CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Mark F. Dalton
        ------------------------------------------------------------------------
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization       USA
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                            114,500
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                        2,342,388
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                       114,500
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                   2,342,388
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   2,489,757
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9        19.6%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    IN
--------------------------------------------------------------------------------

                                     Page 5



CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

             The Tudor BVI Global Portfolio Ltd.
        ------------------------------------------------------------------------
             98-0223576
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization    Cayman Islands
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                        1,820,068
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                   1,820,068
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   1,820,068
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9        14.5%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    CO
--------------------------------------------------------------------------------

                                     Page 6



CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Tudor Arbitrage Partners L.P.
        ------------------------------------------------------------------------
            13-3496979
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization  Delaware
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                          193,126
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                     193,126
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   193,126
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9         1.5%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    PN
--------------------------------------------------------------------------------

                                     Page 7

CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Tudor Proprietary Trading, L.L.C.
        ------------------------------------------------------------------------
            13-3720063
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization  Delaware
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                           25,981
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                      25,981
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person    28,981
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9         0.2%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    OO
--------------------------------------------------------------------------------

                                     Page 8

CUSIP No.         743187106

--------------------------------------------------------------------------------
    1)  Names of Reporting Person

        S.S. or I.R.S. Identification No. of Above Person

            Tudor Global Trading LLC
        ------------------------------------------------------------------------
            13-3862744
        ------------------------------------------------------------------------
--------------------------------------------------------------------------------
    2)  Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)
           ---------------------------------------------------------------------
        (b)         X
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------
    3)  SEC Use Only
--------------------------------------------------------------------------------
    4)  Citizenship or Place of Organization  Delaware
--------------------------------------------------------------------------------
                   (5)  Sole Voting Power                                  0
Number of Shares   -------------------------------------------------------------
Beneficially       (6)  Shared Voting Power                          208,526
Owned by Each      -------------------------------------------------------------
Reporting Person   (7)  Sole Dispositive Power                             0
With               -------------------------------------------------------------
                   (8)  Shared Dispositive Power                     208,526
--------------------------------------------------------------------------------
    9)  Aggregate Amount Beneficially Owned by Each Reporting Person   208,526
--------------------------------------------------------------------------------
   10)  Check if the Aggregate Amount in Row (9) Excludes Certain Shares
        (See Instructions)
--------------------------------------------------------------------------------
   11)  Percent of Class Represented by Amount in Row 9         1.7%
--------------------------------------------------------------------------------
   12)  Type of Reporting Person (See Instructions)    OO
--------------------------------------------------------------------------------

                                     Page 9






Item 1(a).    Name of Issuer:

              Progenics Pharmaceuticals, Inc.

Item 1(b).    Address of Issuer's Principal Executive Offices:

              777 Old Saw Mill River Road
              Tarrytown, NY 10591

Item 2(a).    Name of Person Filing:

              Tudor Investment Corporation ("TIC")
              Tudor Group Holdings LLC ("TGH")
              Paul Tudor Jones, II
              Mark F. Dalton
              The Tudor BVI Global Portfolio Ltd. ("Tudor BVI")
              Tudor Arbitrage Partners L.P. ("TAP")
              Tudor Proprietary Trading, L.L.C. ("TPT")
              Tudor Global Trading LLC ("TGT")

Item 2(b).    Address of Principal Business Office or, if none, Residence:

              The principal business office of each of TIC, TGH, TAP, TPT and
TGT is:

                           1275 King Street
                           Greenwich, CT 06831

              The principal business office of each of Messrs. Jones and Dalton
is:

                           c/o Tudor Investment Corporation
                           1275 King Street
                           Greenwich, CT 06831

              The principal business office of Tudor BVI is:

                           c/o CITCO
                           Kaya Flamboyan 9
                           Curacao, Netherlands Antilles

Item 2(c).    Citizenship:

              TIC is a Delaware corporation
              Tudor BVI is a company organized under the laws of the Cayman
              Islands
              Messrs. Jones and Dalton are citizens of the United States
              TAP is a Delaware limited partnership
              TGH, TPT and TGT are Delaware limited liability companies


                                    Page 10


Item 2(d).    Title of Class of Securities:

              Common Stock

Item 2(e).    CUSIP Number:

              743187106

Item 3.       If this statement is filed pursuant to Rules 13d-1(b), or
              13d-2(b), check whether the person filing is a:

         (a)  [ ] Broker or Dealer registered under Section 15 of the Act
         (b)  [ ] Bank as defined in section 3(a)(6) of the Act
         (c)  [ ] Insurance Company as defined in Section 3(a)(19) of the Act
         (d)  [ ] Investment Company registered under Section 8 of the
                  Investment Company Act
         (e)  [ ] Investment Adviser registered under section 203 of the
                  Investment Advisers Act of 1940
         (f)  [ ] Employment Benefit Plan, Pension Fund which is subject to the
                  provisions of the Employee Retirement Income Security Act of
                  1974 or Endowment Fund; see ss.240.13d-1(b)(1)(ii)(F)
         (g)  [ ] Parent Holding Company, in accordance with
                  ss.240.13d-1(b)(1)(ii)(G) (Note: See Item 7)
         (h)  [ ] Group, in accordance with ss.240.13d-1(b)(1)(ii)(H)


                                    Page 11



Item 4.  Ownership (as of December 31, 2001).

         (a)  Amount Beneficially Owned:  See Item 9 of cover pages

         (b)  Percent of Class:  See Item 11 of cover pages

         (c)  Number of shares as to which such person has:

              (i)   sole power to vote or to direct the vote
                    See Item 5 of cover pages
                    ------------------------------------------------------------

              (ii)  shared power to vote or to direct the vote
                    See Item 6 of cover pages
                    ------------------------------------------------------------

              (iii) sole power to dispose or to direct the disposition of
                    See Item 7 of cover pages
                    ------------------------------------------------------------

              (iv)  shared power to dispose or to direct the disposition of
                    See Item 8 of cover pages
                    ------------------------------------------------------------

         Tudor BVI is the direct beneficial owner of 1,765,468 shares of common
stock ("Shares") and 54,600 warrants ("Warrants" and together with Shares,
"Securities") to purchase Shares. TAP is the direct beneficial owner of 193,126
Shares. TPT is the direct beneficial owner of 25,981. TGT is the direct
beneficial owner of 15,400 Warrants.

         Because TIC provides investment advisory services to Tudor BVI, TIC may
be deemed to beneficially own the Securities owned by Tudor BVI. TIC expressly
disclaims beneficial ownership of such Securities. TGH holds a majority of the
equity interests of TGT and indirectly holds a majority of the membership
interests of TPT. TGH is also the sole limited partner of TAP. TGH expressly
disclaims beneficial ownership of the Securities beneficially owned by each of
such entities. TGT, as the sole general partner of TAP may be deemed to
beneficially own the Securities owned by TAP, and Mr. Dalton, as the sole
general partner of D.F. Partners, a New York limited partnership, may be deemed
to beneficially own the Securities owned by such entity. Each of TGT and Mr.
Dalton expressly disclaim beneficial ownership of such Securities. Mr. Jones is
the Chairman and principal equity owner of TIC and TGH. Mr. Jones expressly
disclaims beneficial ownership of the Securities beneficially owned, or deemed
beneficially owned, by such entities. Mr. Dalton is the President and an equity
owner of TIC and TGH. Mr. Dalton expressly disclaims beneficial ownership of the
Securities beneficially owned, or deemed beneficially owned, by such entities.

         The Shares reported herein under Items 5 and 7 of Mr. Jones' cover page
include 4,600 Shares held directly by Mr. Jones' individual retirement account.
The Shares reported herein under Items 5 and 7 of Mr. Dalton's cover page
include 30,000 immediately exercisable options.


Item 5.  Ownership of Five Percent or Less of a Class.

              Not applicable


                                    Page 12


Item 6.  Ownership of More than Five Percent on Behalf of Another Person.

              Not applicable

Item 7.  Identification  and  Classification of the Subsidiary Which Acquired
         the Security Being Reported on By the Parents Holding Company.

              Not applicable

Item 8.  Identification and Classification of Members of the Group.

              See cover pages

Item 9.  Notice of Dissolution of Group.

              Not applicable



                                    Page 13




Item 10. Certification.

              Not applicable

              After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.


                               Dated: February 12, 2002

                               TUDOR INVESTMENT CORPORATION


                               By:          /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel

                               TUDOR GROUP HOLDINGS LLC


                               By:          /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel



                                            /s/ Paul Tudor Jones, II
                               -------------------------------------------------
                                            Paul Tudor Jones, II



                                            /s/ Mark F. Dalton
                               -------------------------------------------------
                                            Mark F. Dalton

                               THE TUDOR BVI GLOBAL PORTFOLIO LTD.

                               By:  Tudor Investment Corporation,
                                    Trading Advisor


                               By:          /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel


                                     Page 14



                               TUDOR ARBITRAGE PARTNERS L.P.

                               By:  Tudor Global Trading LLC,
                                    General Partner


                               By:          /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel

                               TUDOR PROPRIETARY TRADING, L.L.C.


                               By:          /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel

                               TUDOR GLOBAL TRADING LLC


                               By:         /s/ Stephen N. Waldman
                                  ----------------------------------------------
                                  Stephen N. Waldman
                                  Vice President and Associate General Counsel


                                     Page 15