Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-7486         

        Nuveen Maryland Premium Income Municipal Fund         
(Exact name of registrant as specified in charter)

Nuveen Investments
        333 West Wacker Drive, Chicago, Illinois 60606         

(Address of principal executive offices) (Zip code)


Kevin J. McCarthy Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         

(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            5/31          

Date of reporting period:         8/31/08         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget ("OMB") control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

    Portfolio of Investments (Unaudited)             
    Nuveen Maryland Premium Income Municipal Fund (NMY)             
    August 31, 2008             
Principal        Optional Call         
Amount (000)    Description (1)    Provisions (2)    Ratings (3)    Value 

    Consumer Discretionary – 2.8% (1.8% of Total Investments)             
$         4,825    Baltimore, Maryland, Senior Lien Convention Center Hotel Revenue Bonds, Series 2006A, 5.250%,    9/16 at 100.00    BBB–   $   4,144,142 
     9/01/39 – XLCA Insured             

    Consumer Staples – 1.8% (1.2% of Total Investments)             
2,885    Puerto Rico, The Children’s Trust Fund, Tobacco Settlement Asset-Backed Refunding Bonds,    5/12 at 100.00    BBB    2,683,714 
     Series 2002, 5.375%, 5/15/33             

    Education and Civic Organizations – 16.2% (10.6% of Total Investments)             
1,250    Frederick County, Maryland, Educational Facilities Revenue Bonds, Mount Saint Mary’s College,    9/16 at 100.00    BBB–    1,182,638 
     Series 2006, 5.625%, 9/01/38             
1,000    Hartford County, Maryland, Economic Development Revenue Bonds, Battelle Memorial Institute,    4/14 at 100.00    A+    1,010,070 
     Series 2004, 5.250%, 4/01/34             
    Maryland Economic Development Corporation, Utility Infrastructure Revenue Bonds, University of             
    Maryland – College Park, Series 2001:             
980     5.375%, 7/01/15 – AMBAC Insured    7/11 at 100.00    AA    1,035,586 
980     5.375%, 7/01/16 – AMBAC Insured    7/11 at 100.00    AA    1,035,586 
    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Bullis School,             
    Series 2000:             
750     5.250%, 7/01/25 – FSA Insured    1/11 at 101.00    AAA    773,370 
500     5.250%, 7/01/30 – FSA Insured    1/11 at 101.00    AAA    506,730 
1,250    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Goucher College,    7/14 at 100.00    A–    1,234,913 
     Series 2004, 5.125%, 7/01/34             
1,825    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Maryland Institute    6/16 at 100.00    Baa1    1,662,466 
     College of Art, Series 2006, 5.000%, 6/01/30             
1,365    Montgomery County Revenue Authority, Maryland, Lease Revenue Bonds, Montgomery College Arts    5/15 at 100.00    A1    1,434,943 
     Center Project, Series 2005A, 5.000%, 5/01/19             
9,445    Morgan State University, Maryland, Student Tuition and Fee Revenue Refunding Bonds, Academic    No Opt. Call    AA    10,828,029 
     Fees and Auxiliary Facilities, Series 1993, 6.100%, 7/01/20 – MBIA Insured             
1,685    University of Maryland, Auxiliary Facility and Tuition Revenue Bonds, Series 2006A,    10/16 at 100.00    AA+    1,782,494 
     5.000%, 10/01/22             
    Westminster, Maryland, Educational Facilities Revenue Bonds, McDaniel College, Series 2006:             
910     5.000%, 11/01/31    11/16 at 100.00    BBB+    838,438 
850     4.500%, 11/01/36    11/16 at 100.00    BBB+    690,430 

22,790    Total Education and Civic Organizations            24,015,693 

    Health Care – 24.0% (15.7% of Total Investments)             
1,525    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Calvert Memorial    7/14 at 100.00    A2    1,532,046 
     Hospital, Series 2004, 5.500%, 7/01/36             
3,250    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Carroll County    7/12 at 100.00    Baa1    3,258,223 
     General Hospital, Series 2002, 5.800%, 7/01/32             
400    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Carroll Hospital    7/16 at 100.00    Baa1    352,160 
     Center, Series 2006, 5.000%, 7/01/40             
1,665    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Civista Medical    7/14 at 100.00    A3    1,425,690 
     Center, Series 2005, 5.000%, 7/01/37 – RAAI Insured             
1,740    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Doctors Community    7/17 at 100.00    Baa2    1,565,008 
     Hospital, Series 2007A, 5.000%, 7/01/29             
1,400    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Frederick Memorial    7/12 at 100.00    Baa1    1,317,358 
     Hospital, Series 2002, 5.125%, 7/01/35             
1,500    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Greater Baltimore    7/11 at 100.00    A+    1,408,875 
     Medical Center, Series 2001, 5.000%, 7/01/34 – MBIA Insured             
1,000    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Johns Hopkins    1/09 at 101.00    AA    1,011,480 
     Hospital, Howard County General Hospital Acquisition, Series 1998, 5.000%, 7/01/19 –             
     MBIA Insured             
1,430    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Johns Hopkins    7/14 at 100.00    AA    1,475,145 
     Hospital, Series 2004, Inverse 1003, 10.840%, 7/01/33 (IF)             
2,000    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Kaiser Permanente    6/09 at 101.00    A+    2,036,700 
     System, Series 1998A, 5.375%, 7/01/15             
3,800    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Kennedy Krieger    7/13 at 100.00    Baa3    3,605,174 
     Institute, Series 2003, 5.500%, 7/01/33             
1,175    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, LifeBridge Health    7/17 at 100.00    AAA    1,201,038 
     System, Series 2008, 5.000%, 7/01/28 – AGC Insured             
1,750    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, MedStar Health,    8/14 at 100.00    A–    1,760,500 
     Series 2004, 5.375%, 8/15/24             
3,310    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, MedStar Health,    5/16 at 100.00    AAA    3,315,329 
     Series 2007, 5.250%, 5/15/46 – BHAC Insured             
    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Mercy Medical             
    Center Project, Series 2007A:             
1,010     5.000%, 7/01/37    7/17 at 100.00    BBB    885,922 
670     5.500%, 7/01/42    7/17 at 100.00    BBB    629,472 
1,700    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Peninsula Regional    7/16 at 100.00    A    1,610,716 
     Medical Center, Series 2006, 5.000%, 7/01/36             
3,250    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Union Hospital of    7/12 at 100.00    A3    3,265,275 
     Cecil County, Series 2002, 5.625%, 7/01/32             
1,000    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, University of    7/13 at 100.00    AA    1,005,480 
     Maryland Medical System, Series 2004B, 5.000%, 7/01/24 – AMBAC Insured             
2,395    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Washington County    1/18 at 100.00    BBB–    2,328,682 
     Hospital, Series 2008, 5.750%, 1/01/38             
    Prince George’s County, Maryland, Revenue Bonds, Dimensions Health Corporation, Series 1994:             
420     5.375%, 7/01/14    1/09 at 100.00    B3    368,206 
295     5.300%, 7/01/24    1/09 at 100.00    B3    226,492 

36,685    Total Health Care            35,584,971 

    Housing/Multifamily – 12.1% (7.9% of Total Investments)             
1,450    Maryland Community Development Administration, FNMA Multifamily Development Revenue Bonds,    2/11 at 101.00    Aaa    1,478,174 
     Edgewater Village Apartments, Series 2000B, 5.800%, 8/01/20 (Alternative Minimum Tax)             
2,500    Maryland Community Development Administration, Housing Revenue Bonds, Series 1999A, 5.350%,    1/09 at 101.00    Aa2    2,267,825 
     7/01/41 (Alternative Minimum Tax)             
880    Maryland Community Development Administration, Housing Revenue Bonds, Series 1999B, 6.250%,    1/10 at 100.00    Aa2    883,485 
     7/01/32 (Alternative Minimum Tax)             
1,000    Maryland Economic Development Corporation, Senior Lien Student Housing Revenue Bonds,    10/13 at 100.00    B2    881,970 
     University of Maryland – Baltimore, Series 2003A, 5.625%, 10/01/23             
1,000    Maryland Economic Development Corporation, Student Housing Revenue Bonds, Collegiate Housing    6/09 at 102.00    Baa3    1,022,780 
     Foundation – Salisbury State University, Series 1999A, 6.000%, 6/01/19             
1,145    Maryland Economic Development Corporation, Student Housing Revenue Refunding Bonds, University    6/16 at 100.00    Baa2    1,010,291 
     of Maryland College Park Projects, Series 2006, 5.000%, 6/01/33 – CIFG Insured             
3,830    Montgomery County Housing Opportunities Commission, Maryland, FNMA/FHA-Insured Multifamily    1/09 at 101.00    Aaa    3,818,816 
     Housing Development Bonds, Series 1998A, 5.200%, 7/01/30             
360    Montgomery County Housing Opportunities Commission, Maryland, GNMA/FHA-Insured Multifamily    1/09 at 100.00    Aa2    360,551 
     Housing Revenue Bonds, Series 1995A, 5.900%, 7/01/15             
2,000    Montgomery County Housing Opportunities Commission, Maryland, Multifamily Housing Development    7/10 at 100.00    Aaa    2,028,640 
     Bonds, Series 2000A, 6.100%, 7/01/30             
540    Prince George’s County Housing Authority, Maryland, GNMA Collateralized Mortgage Revenue    9/09 at 102.00    AAA    541,312 
     Bonds, University Landing Apartments, Series 1999, 6.100%, 3/20/41 (Alternative Minimum Tax)             
    Prince George’s County Housing Authority, Maryland, GNMA Collateralized Mortgage Revenue             
    Refunding Bonds, Overlook Apartments, Series 1995A:             
2,000     5.700%, 12/20/15    12/08 at 100.00    AAA    2,002,700 
1,670     5.750%, 12/20/19    12/08 at 100.00    AAA    1,671,620 

18,375    Total Housing/Multifamily            17,968,164 

    Housing/Single Family – 8.9% (5.8% of Total Investments)             
650    Maryland Community Development Administration Department of Housing and Community Development,    3/17 at 100.00    Aa2    594,783 
     Residential Revenue Bonds, Series 2007H, 5.000%, 9/01/27 (Alternative Minimum Tax)             
2,510    Maryland Community Development Administration Department of Housing and Community Development,    9/18 at 100.00    Aa2    2,520,592 
     Residential Revenue Bonds, Series 2008C, 5.375%, 9/01/39 (WI/DD, Settling 9/04/08)             
1,195    Maryland Community Development Administration, Department of Housing and Community    9/15 at 100.00    Aa2    1,088,239 
     Development, Residential Revenue Bonds, Series 2006F, 4.900%, 9/01/26 (Alternative Minimum Tax)             
4,100    Maryland Community Development Administration, Department of Housing and Community    3/16 at 100.00    Aa2    3,722,267 
     Development, Residential Revenue Bonds, Series 2006I, 4.875%, 9/01/26 (Alternative Minimum Tax)             
1,630    Maryland Community Development Administration, Department of Housing and Community    9/16 at 100.00    Aa2    1,434,041 
     Development, Residential Revenue Bonds, Series 2006L, 4.900%, 9/01/31 (Alternative Minimum Tax)             
1,200    Maryland Community Development Administration, Department of Housing and Community    3/17 at 100.00    Aa2    1,024,500 
     Development, Residential Revenue Bonds, Series 2007D, 4.850%, 9/01/37 (Alternative Minimum Tax)             
365    Maryland Community Development Administration, Residential Revenue Bonds, Series 2005E,    9/14 at 100.00    Aa2    312,174 
     4.900%, 9/01/36 (Alternative Minimum Tax)             
600    Maryland Community Development Administration, Residential Revenue Bonds, Series 2006B,    9/15 at 100.00    Aa2    541,902 
     4.750%, 9/01/25 (Alternative Minimum Tax)             
790    Montgomery County Housing Opportunities Commission, Maryland, Single Family Mortgage Revenue    7/15 at 100.00    Aa2    686,534 
     Bonds, Series 2005D, 5.000%, 7/01/36             
1,175    Montgomery County Housing Opportunities Commission, Maryland, Single Family Mortgage Revenue    1/16 at 100.00    Aa2    973,570 
     Bonds, Series 2006B, 4.700%, 7/01/37             
5    Prince George’s County Housing Authority, Maryland, FHLMC/FNMA/GNMA Collateralized Single    8/10 at 100.00    AAA    5,042 
     Family Mortgage Revenue Bonds, Series 2000A, 6.150%, 8/01/19 (Alternative Minimum Tax)             
320    Puerto Rico Housing Finance Authority, Mortgage-Backed Securities Program Home Mortgage    6/13 at 100.00    AAA    276,435 
     Revenue Bonds, Series 2003A, 4.875%, 6/01/34 (Alternative Minimum Tax)             

14,540    Total Housing/Single Family            13,180,079 

    Industrials – 1.3% (0.8% of Total Investments)             
2,010    Maryland Economic Development Corporation, Solid Waste Disposal Revenue Bonds, Waste    4/12 at 101.00    BBB    1,847,853 
     Management Inc., Series 2002, 4.600%, 4/01/16 (Alternative Minimum Tax)             

    Long-Term Care – 2.8% (1.8% of Total Investments)             
2,455    Baltimore County, Maryland, Revenue Bonds, Oak Crest Village, Series 2007A, 5.000%, 1/01/37    1/17 at 100.00    BBB+    2,217,822 
1,000    Carroll County, Maryland, Revenue Refunding Bonds, EMA Obligated Group, Series 1999A, 5.625%,    1/09 at 101.00    BBB+    1,004,800 
     1/01/25 – RAAI Insured             
1,065    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Mercy Ridge    7/17 at 100.00    BBB+    893,652 
     Retirement Community, Series 2007, 4.750%, 7/01/34             

4,520    Total Long-Term Care            4,116,274 

    Tax Obligation/General – 34.8% (22.7% of Total Investments)             
2,030    Anne Arundel County, Maryland, General Obligation Bonds, Series 2004, 5.000%, 4/01/16    4/14 at 100.00    AAA    2,208,011 
    Anne Arundel County, Maryland, General Obligation Bonds, Series 2006:             
1,310     5.000%, 3/01/21    3/16 at 100.00    AAA    1,392,465 
1,000     5.000%, 3/01/21    3/16 at 100.00    AAA    1,062,950 
685    Anne Arundel County, Maryland, Water and Sewer Revenue Bonds, Series 2006, 5.000%, 3/01/17    3/16 at 100.00    AAA    754,637 
    Baltimore County, Maryland, Metropolitan District Special Assessment Bonds, 67th Issue:             
2,500     5.000%, 6/01/25    6/11 at 101.00    AAA    2,561,775 
3,500     5.000%, 6/01/26    6/11 at 101.00    AAA    3,570,490 
1,000    Baltimore, Maryland, Consolidated General Obligation Public Improvement Bonds, Series 1989B,    No Opt. Call    AA–    1,006,710 
     7.150%, 10/15/08             
1,540    Baltimore, Maryland, General Obligation Consolidated Public Improvement Bonds, Series 2004A,    10/14 at 100.00    AA    1,598,289 
     5.000%, 10/15/22 – AMBAC Insured             
700    Carroll County, Maryland, Consolidated Public Improvement Bonds, Series 2005A, 5.000%, 12/01/16    12/15 at 100.00    AA    776,909 
    Charles County, Maryland, Consolidated General Obligation Public Improvement Bonds,             
    Series 2006:             
2,185     5.000%, 3/01/14    No Opt. Call    AA    2,409,574 
820     5.000%, 3/01/16    No Opt. Call    AA    912,004 
1,500    Frederick County, Maryland, General Obligation Public Facilities Bonds, Series 2006,    No Opt. Call    AA+    1,646,700 
     5.000%, 11/01/20             
    Howard County, Maryland, Consolidated Public Improvement Bonds, Series 2004B:             
1,625     5.000%, 8/15/17    2/14 at 100.00    AAA    1,763,938 
1,180     5.000%, 8/15/19    2/14 at 100.00    AAA    1,259,119 
1,725    Howard County, Maryland, Metropolitan District Refunding Bonds, Series 2002A, 5.250%, 8/15/18    2/12 at 100.00    AAA    1,825,740 
1,190    Maryland National Capital Park Planning Commission, Prince George’s County, General Obligation    1/14 at 100.00    AAA    1,285,117 
     Bonds, Park Acquisition and Development, Series 2004EE-2, 5.000%, 1/15/17             
3,000    Montgomery County, Maryland, Consolidated General Obligation Public Improvement Bonds, Series    No Opt. Call    AAA    3,344,820 
     2005A, 5.000%, 7/01/15             
3,520    Montgomery County, Maryland, Consolidated General Obligation Public Improvement Bonds, Series    No Opt. Call    AAA    3,935,182 
     2006, 5.000%, 5/01/16             
    Montgomery County, Maryland, Consolidated General Obligation Public Improvement Refunding             
    Bonds, Series 2001:             
1,750     5.250%, 10/01/13    10/11 at 101.00    AAA    1,894,585 
2,000     5.250%, 10/01/18    10/11 at 101.00    AAA    2,135,620 
2,000    Prince George’s County, Maryland, General Obligation Consolidated Public Improvement Bonds,    9/12 at 101.00    AAA    2,027,460 
     Series 2002, 4.100%, 9/15/19             
5,770    Prince George’s County, Maryland, General Obligation Consolidated Public Improvement Bonds,    10/13 at 100.00    AAA    6,116,198 
     Series 2003A, 5.000%, 10/01/18             
    Washington Suburban Sanitary District, Montgomery and Prince George’s Counties, Maryland,             
    Sewerage Disposal Bonds, Series 2005:             
2,000     5.000%, 6/01/16    6/15 at 100.00    AAA    2,210,020 
1,235     5.000%, 6/01/23    6/15 at 100.00    AAA    1,297,701 
1,235     5.000%, 6/01/24    6/15 at 100.00    AAA    1,293,996 
1,235     5.000%, 6/01/25    6/15 at 100.00    AAA    1,290,291 

48,235    Total Tax Obligation/General            51,580,301 

    Tax Obligation/Limited – 15.2% (9.9% of Total Investments)             
300    Baltimore, Maryland, Special Obligation Bonds, North Locust Point Project, Series 2005,    9/15 at 101.00    N/R    259,404 
     5.500%, 9/01/34             
340    Frederick County, Maryland, Lake Linganore Village Community Development Special Obligation    7/10 at 102.00    BBB+    338,331 
     Bonds, Series 2001A, 5.700%, 7/01/29 – RAAI Insured             
900    Hyattsville, Maryland, Special Obligation Bonds, University Town Center Project, Series 2004,    7/14 at 102.00    N/R    806,157 
     5.750%, 7/01/34             
    Maryland Department of Transportation, Certificates of Participation, Mass Transit             
    Administration Project, Series 2000:             
875     5.500%, 10/15/19 (Alternative Minimum Tax)    10/10 at 101.00    AA+    898,415 
925     5.500%, 10/15/20 (Alternative Minimum Tax)    10/10 at 101.00    AA+    935,009 
4,250    Maryland Department of Transportation, Consolidated Transportation Revenue Bonds, Series 2002,    No Opt. Call    AAA    4,853,456 
     5.500%, 2/01/16             
1,875    Maryland Economic Development Corporation, Lease Revenue Bonds, Department of Transportation    6/12 at 100.50    AA+    2,002,763 
     Headquarters Building, Series 2002, 5.375%, 6/01/19             
1,700    Maryland Stadium Authority, Lease Revenue Bonds, Montgomery County Conference Center    6/13 at 100.00    AA+    1,759,517 
     Facilities, Series 2003, 5.000%, 6/15/24             
1,000    Montgomery County, Maryland, Lease Revenue Bonds, Metrorail Garage, Series 2002,    6/12 at 100.00    AA    1,043,990 
     5.000%, 6/01/21             
675    Montgomery County, Maryland, Special Obligation Bonds, West Germantown Development District,    7/12 at 101.00    A    657,956 
     Senior Series 2002A, 5.500%, 7/01/27 – RAAI Insured             
635    New Baltimore City Board of School Commissioners, Maryland, School System Revenue Bonds,    11/10 at 100.00    AA+    668,490 
     Series 2000, 5.125%, 11/01/15             
    Puerto Rico Highway and Transportation Authority, Highway Revenue Bonds, Series 2007N:             
1,000     5.500%, 7/01/29 – AMBAC Insured    No Opt. Call    Aaa    1,033,940 
2,500     5.250%, 7/01/31 – AMBAC Insured    No Opt. Call    AA    2,486,650 
1,000     5.250%, 7/01/33 – MBIA Insured    No Opt. Call    AA    993,060 
2,100    Puerto Rico Municipal Finance Agency, Series 2002A, 5.250%, 8/01/21 – FSA Insured    8/12 at 100.00    AAA    2,150,673 
1,500    Puerto Rico, Highway Revenue Bonds, Highway and Transportation Authority, Series 2003AA,    No Opt. Call    AA    1,563,975 
     5.500%, 7/01/19 – MBIA Insured             

21,575    Total Tax Obligation/Limited            22,451,786 

    Transportation – 4.6% (3.0% of Total Investments)             
1,060    Baltimore, Maryland, Revenue Refunding Bonds, Parking System Facilities, Series 1998A, 5.250%,    No Opt. Call    A2    1,148,902 
     7/01/17 – FGIC Insured             
4,335    Maryland Transportation Authority, Revenue Bonds, Transportation Facilities Projects, Series    7/17 at 100.00    AAA    4,462,709 
     2007, 5.000%, 7/01/30 – FSA Insured (UB)             
2,075    Puerto Rico Ports Authority, Special Facilities Revenue Bonds, American Airlines Inc., Series    12/08 at 100.00    CCC+    1,166,358 
     1996A, 6.250%, 6/01/26 (Alternative Minimum Tax)             

7,470    Total Transportation            6,777,969 

    U.S. Guaranteed – 21.5% (14.0% of Total Investments) (4)             
2,000    Baltimore, Maryland, Revenue Refunding Bonds, Water Projects, Series 1998A, 5.000%, 7/01/28 –    No Opt. Call    AA (4)    2,112,880 
     FGIC Insured (ETM)             
2,000    Baltimore, Maryland, Revenue Refunding Bonds, Water System Projects, Series 1994A, 5.000%,    No Opt. Call    AA (4)    2,144,020 
     7/01/24 – FGIC Insured (ETM)             
1,245    Baltimore, Maryland, Wastewater Project Revenue Bonds, Series 2006C, 5.000%, 7/01/31    7/16 at 100.00    AA (4)    1,385,087 
     (Pre-refunded 7/01/16) – AMBAC Insured             
    Frederick County, Maryland, Educational Facilities Revenue Bonds, Mount St. Mary’s College,             
    Series 2001A:             
200     5.750%, 9/01/25 (Pre-refunded 3/01/10)    3/10 at 101.00    BBB– (4)    212,596 
200     5.800%, 9/01/30 (Pre-refunded 3/01/10)    3/10 at 101.00    BBB– (4)    212,744 
3,000    Frederick County, Maryland, General Obligation Public Facilities Bonds, Series 1999, 5.250%,    7/09 at 101.00    AAA    3,117,960 
     7/01/18 (Pre-refunded 7/01/09)             
275    Frederick County, Maryland, Lake Linganore Village Community Development Special Obligation    7/10 at 102.00    BBB+ (4)    297,919 
     Bonds, Series 2001A, 5.700%, 7/01/29 (Pre-refunded 7/01/10) – RAAI Insured             
1,860    Gaithersburg, Maryland, Hospital Facilities Revenue Refunding and Improvement Bonds, Shady    No Opt. Call    AAA    2,014,436 
     Grove Adventist Hospital, Series 1995, 6.500%, 9/01/12 – FSA Insured (ETM)             
575    Howard County, Maryland, Consolidated Public Improvement Refunding Bonds, Series 2002A,    2/12 at 100.00    AAA    626,514 
     5.250%, 8/15/18 (Pre-refunded 2/15/12)             
    Maryland Economic Development Corporation, Health and Mental Hygiene Providers Revenue Bonds,             
    Series 1996A:             
870     7.625%, 4/01/21 (Pre-refunded 4/01/11)    4/11 at 102.00    N/R (4)    987,459 
660     7.625%, 4/01/21 (Pre-refunded 4/01/11)    4/11 at 102.00    N/R (4)    749,107 
2,250    Maryland Economic Development Corporation, Student Housing Revenue Bonds, Collegiate Housing    6/09 at 102.00    Baa2 (4)    2,360,520 
     Foundation – College Park, Series 1999A, 5.750%, 6/01/24 (Pre-refunded 6/01/09)             
3,200    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Helix Health,    No Opt. Call    AA (4)    3,431,616 
     Series 1997, 5.000%, 7/01/27 – AMBAC Insured (ETM)             
3,125    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, Howard County    1/08 at 100.00    Aaa    3,194,563 
     General Hospital, Series 1993, 5.500%, 7/01/25 (ETM)             
2,040    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, LifeBridge Health    7/14 at 100.00    A (4)    2,240,144 
     System, Series 2004A, 5.125%, 7/01/34 (Pre-refunded 7/01/14)             
1,500    Maryland Health and Higher Educational Facilities Authority, Revenue Bonds, University of    7/12 at 100.00    A (4)    1,670,895 
     Maryland Medical System, Series 2002, 6.000%, 7/01/22 (Pre-refunded 7/01/12)             
195    Maryland Transportation Authority, Revenue Refunding Bonds, Transportation Facilities    No Opt. Call    AAA    225,046 
     Projects, First Series 1978, 6.800%, 7/01/16 (ETM)             
1,000    Puerto Rico Infrastructure Financing Authority, Special Obligation Bonds, Series 2000A,    10/10 at 101.00    AAA    1,044,470 
     5.500%, 10/01/20             
1,000    Puerto Rico, Highway Revenue Bonds, Highway and Transportation Authority, Series 1996Y,    7/16 at 100.00    Aaa    1,154,180 
     5.500%, 7/01/36 (Pre-refunded 7/01/16)             
385    Puerto Rico, The Children’s Trust Fund, Tobacco Settlement Asset-Backed Bonds, Series 2000,    7/10 at 100.00    AAA    402,922 
     5.750%, 7/01/20 (Pre-refunded 7/01/10)             
2,000    Virgin Islands Public Finance Authority, Gross Receipts Taxes Loan Note, Series 1999A, 6.500%,    10/10 at 101.00    BBB+ (4)    2,194,780 
     10/01/24 (Pre-refunded 10/01/10)             

29,580    Total U.S. Guaranteed            31,779,858 

    Utilities – 4.0% (2.6% of Total Investments)             
2,500    Maryland Energy Financing Administration, Revenue Bonds, AES Warrior Run Project, Series 1995,    9/08 at 100.00    N/R    2,436,150 
     7.400%, 9/01/19 (Alternative Minimum Tax)             
3,500    Puerto Rico Electric Power Authority, Power Revenue Bonds, Series 2004PP, 5.000%, 7/01/22 –    7/14 at 100.00    A3    3,475,605 
     FGIC Insured             

6,000    Total Utilities            5,911,755 

    Water and Sewer – 3.4% (2.2% of Total Investments)             
1,045    Baltimore, Maryland, Revenue Refunding Bonds, Water System Projects, Series 1994A, 5.000%,    No Opt. Call    AA    1,089,193 
     7/01/24 – FGIC Insured             
1,655    Baltimore, Maryland, Wastewater Project Revenue Bonds, Series 2006C, 5.000%, 7/01/31 –    7/16 at 100.00    AA    1,696,954 
     AMBAC Insured             
1,260    Baltimore, Maryland, Wastewater Project Revenue Bonds, Series 2007D, 5.000%, 7/01/32 –    7/17 at 100.00    AA    1,263,490 
     AMBAC Insured             
860    Maryland Water Quality Financing Administration, Revolving Loan Fund Revenue Bonds, Series    No Opt. Call    AAA    959,889 
     2005A, 5.000%, 9/01/15             
4,820    Total Water and Sewer        5,009,526 

$       224,310    Total Investments (cost $227,174,582) – 153.4%        227,052,085 


    Floating Rate Obligations – (2.2)%        (3,250,000)

    Other Assets Less Liabilities – 2.2%        3,313,998 

    Preferred Shares, at Liquidation Value – (53.4)% (5)        (79,100,000)

    Net Assets Applicable to Common Shares – 100%       $  148,016,083 



(1)    All percentages shown in the Portfolio of Investments are based on net assets applicable to Common 
    shares unless otherwise noted. 
(2)    Optional Call Provisions: Dates (month and year) and prices of the earliest optional call or redemption. 
    There may be other call provisions at varying prices at later dates. Certain mortgage-backed securities 
    may be subject to periodic principal paydowns. 
(3)    Ratings: Using the higher of Standard & Poor’s Group (“Standard & Poor’s”) or Moody’s Investor Service, 
    Inc. (“Moody’s”) rating. Ratings below BBB by Standard & Poor’s or Baa by Moody’s are considered to be 
    below investment grade. 
    The Portfolio of Investments may reflect the ratings on certain bonds insured by ACA, AMBAC, CIFG, FGIC, 
    MBIA, RAAI and XLCA as of August 31, 2008. Subsequent to August 31, 2008, and during the period this 
    Portfolio of Investments was prepared, there may have been reductions to the ratings of certain bonds 
    resulting from changes to the ratings of the underlying insurers both during the period and after period end. 
    Such reductions would likely reduce the effective rating of many of the bonds insured by that insurer or 
    insurers presented at period end. 
(4)    Backed by an escrow or trust containing sufficient U.S. Government or U.S. Government agency securities 
    which ensure the timely payment of principal and interest. Such investments are normally considered to 
    be equivalent to AAA rated securities. 
(5)    Preferred Shares, at Liquidation Value as a percentage of total investments is (34.8)%. 
N/R    Not rated. 
WI/DD    Purchased on a when-issued or delayed delivery basis. 
(ETM)    Escrowed to maturity. 
(IF)    Inverse floating rate investment. 
(UB)    Underlying bond of an inverse floating rate trust reflected as a financing transaction pursuant to the 
    provisions of SFAS No. 140. 

Fair Value Measurements

During the current fiscal period, the Fund adopted the provisions of Statement of Financial Accounting Standards No. 157, Fair Value Measurements (SFAS 157). SFAS 157 defines fair value, establishes a framework for measuring fair value in generally accepted accounting principles, and expands disclosure about fair value measurements. In determining the value of the Fund’s investments various inputs are used. These inputs are summarized in the three broad levels listed below:

Level 1 – Quoted prices in active markets for identical securities.

Level 2 – Other significant observable inputs (including quoted prices for similar securities, interest rates, prepayment speeds, credit risk, etc.).

Level 3 – Significant unobservable inputs (including management’s assumptions in determining the fair value of investments).

The inputs or methodology used for valuing securities are not an indication of the risk associated with investing in those securities.

The following is a summary of the Fund’s fair value measurements as of August 31, 2008:

    Level 1    Level 2    Level 3    Total 

Investments    $ —    $227,052,085    $ —    $227,052,085 


Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to timing differences in recognizing taxable market discount, timing differences in recognizing certain gains and losses on investment transactions and the treatment of investments in inverse floating rate transactions subject to SFAS No.140. To the extent that differences arise that are permanent in nature, such amounts are reclassified within the capital accounts on the Statement of Assets and Liabilities presented in the annual report, based on their federal tax basis treatment; temporary differences do not require reclassification. Temporary and permanent differences do not impact the net asset value of the Fund.

At August 31, 2008, the cost of investments was $223,987,321.

Gross unrealized appreciation and gross unrealized depreciation of investments at August 31, 2008, were as follows:


Gross unrealized:     
  Appreciation    $ 6,467,839 
  Depreciation    (6,652,949)

Net unrealized appreciation (depreciation) of investments    $   (185,110)



Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: See EX-99 CERT attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Maryland Premium Income Municipal Fund         

By (Signature and Title)          /s/ Kevin J. McCarthy                    
                                                  Kevin J. McCarthy
                                                  Vice President and Secretary

Date         October 30, 2008        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)         /s/ Gifford R. Zimmerman                    
                                                 Gifford R. Zimmerman
                                                 Chief Administrative Officer (principal executive officer) 

Date         October 30, 2008        

By (Signature and Title)         /s/ Stephen D. Foy                              
                                                 Stephen D. Foy
                                                 Vice President and Controller (principal financial officer) 

Date        October 30, 2008